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The objective of this study was to examine the association between TNF-α serum levels and -308G>A and -238G>A ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 15 (2): gmr.15028199 polymorphisms in the corresponding gene by comparing healthy subjects to colorectal cancer (CRC) patients from a Mexican population. Serum levels of TNF-α were found to significantly differ between CRC patients and controls (P = 0.001), but no relationship between the -308G>A and -238G>A polymorphismsdoi:10.4238/gmr.15028199 pmid:27421001 fatcat:ksu575rj3fdwtbknxvxn4ai6ya