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Introduction and Aims: It is beyond any doubt that nicotine yield in cigarettes as determined using standard ISO method bears almost no relation to smokers' actual intake. However, the ISO method is still in use in many countries where the government is responsible for controlling and monitoring cigarette quality. The aim of the study was to measure the nicotine yield in single cigarettes and to evaluate their statistical distribution among the same brand. Materials and methods: Nicotine yieldsdoi:10.21101/cejph.a3721 fatcat:2fbiyxfrgjb5lih6lnlyrzy52q