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A key issue in the study of protein signaling networks is understanding the relationships among proteins in the network. Understanding these relationships in the context of a network is one of the major challenges for modern biology [2, 6] . In the laboratory a time series of protein modification measurements is taken in order that relationships among the activations can be conjectured. Laubenbacher and Stigler  have developed an algorithm to make conjectures concerning gene expression.doi:10.1145/1167350.1167382 dblp:conf/ACMse/AllenFJT05 fatcat:rlj564kbpbhqbhe35zs4kxpgdq