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Oral versus non-oral hormone replacement therapy: how important is the route of administration?
2007
Ginekologia Polska
Although there are differences in the pharmacokinetic profiles of oral and non-oral routes of administration the clinical relevance of these differences remains to be determined. Likewise, there are differences in the metabolic and haemostatic effects of different routes of administration of oestrogen but these may have clinical relevance. For some parameters, such as lipids and lipoproteins, glucose and insulin metabolism, there are greater benefits from oral administration; for others,
pmid:17915406
fatcat:zkloob6eubcjvah3npjxcwa5ka