Oral management of adult patients undergoing hematopoietic stem cell transplantation Oral management of adult patients undergoing hematopoietic stem cell transplantation

P Bollero, P Passarelli, A D'addona, G Pasquantonio, M Mancini, R Condò, L Cerroni
unpublished
Chemotherapy and hematopoiet-ic stem cell transplantation (HSCT) are the current treatments for patients with hematological diseases; they result in myelosuppression, and increase the susceptibility of patients to severe infections. The oral cavity is a potential site of complications in HSCT patients, because it is the entrance for agents that can cause system-ic infections; it is one of the most frequent locations for side effects deriving from conditioning therapy. The importance of dental
more » ... ortance of dental pre-chemo-therapy and transplant prescription is often stressed, since both therapies depress the immune system and platelets, making each intervention at this stage a high risk. The aim of this article is to review the potential complications of HSCT, and to extrapolate from the scientific literature the treatments and timeframes in which dental therapies can be performed, avoiding important risks for patients.
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