Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography

Shanhui Fan, Yong Sun, Cuixia Dai, Haihua Zheng, Qiushi Ren, Shuliang Jiao, Chuanqing Zhou
2014 Journal of Biomedical Optics  
To research retinal stretching or distortion with accommodation, accommodation-induced changes in retinal thickness (RT) in the macular area were investigated in a population of young adults (n ¼ 23) by using a dual-channel spectral domain optical coherence tomography (SD-OCT) system manufactured in-house for this study. This dual-channel SD-OCT is capable of imaging the cornea and retina simultaneously with an imaging speed of 24 kHz A-line scan rate, which can provide the anatomical
more » ... natomical dimensions of the eye, including the RT and axial length. Thus, the modification of the RT with accommodation can be calculated. A significant decrease in the RT (13.50 AE 1.25 μm) was observed during maximum accommodation. In the 4 mm × 4 mm macular area centered at the fovea, we did not find a significant quadrant-dependent difference in retinal volume change, which indicates that neither retinal stretching nor distortion was quadrant-dependent during accommodation. We speculate that the changes in RT with maximum accommodation resulted from accommodation-induced ciliary muscle contractions.
doi:10.1117/1.jbo.19.9.096012 pmid:25233144 fatcat:7q3jrg6c6bfv3e3zohpooh2qju