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Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
2016
Nature Neuroscience
Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between schizophrenia cases and healthy individuals. As common genetic associations are emerging for both schizophrenia and brain imaging phenotypes, we can now use genome-wide data to investigate genetic overlap. Here we integrated results from common variant studies of schizophrenia (33,636 cases, 43,008 controls) and volumes of several (mainly subcortical) brain
doi:10.1038/nn.4228
pmid:26854805
pmcid:PMC4852730
fatcat:d2celhhusravto6fr7g3fxvfqi