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VIIth International Congress on Thrombosis and Haemostasis
20 dogs(between 15-20kgs weight) were protected against experimental vein thrombosis using either heparin or M945 (orally absorbable, MW10-20.000 mucopolisacarid. Syntex Arg). Vein thrombosis was induced using XIIa-XIa con centrates, and the minimal concentration to be infused to each animal, that would induce a 4/4 size thrombous was determined. Stasis was induced with atraumatic clamps, and yugular and femoral veins were used. Heparin and M945 were compared in their KCCT, TT effects, relateddoi:10.1055/s-0039-1687295 fatcat:onrr2xc2czajphv5utjfj2kkeq