Digital pacinian neuroma in a patient with myeloma

Yosra Soua, Kamar Belhareth, Hayet Akkari
2020 Nasza Dermatologia Online  
We present a case of Pacinian Neuroma (PN) associated with multiple myeloma (MM) in a 57-year-old man with a 6-month history of painful swelling of his fingers. Physical examination revealed definite palpable nodules and moderate swelling over the first phalanx of all his fingers. A biopsy confirmed the diagnosis of PN. The patient reported chronic back pain. Radiologically, a severe demineralization was found. MM was suspected. The results of complete blood count and biochemistry panels were
more » ... istry panels were within normal limits. Otherwise, immunoelectrophoresis demonstrated monoclonal light chains in blood and urine. Bone marrow biopsy was consistent with MM. The patient successfully underwent an autologous stem cell transplant with good response. A slight decrease in the size in PN was noted. To the best of our knowledge, no case of PN associated with MM had been reported. This occurrence may be accidental. However, further studies are required in order to explain this association.
doi:10.7241/ourd.20202.15 fatcat:pu6zyjjptfagjp56d2iygquzye