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Considerable research effort has been reported in cost-optimal operation of heat exchanger network. However, most of them neglect the pressure drop influence and assume constant film heat transfer coefficients. Pressure drop of streams are important influencing factors for the performance of heat exchanger network operation. In this paper, a general cost-optimal operation model considering pressure drop constraints and removing the assumption of constant film heat transfer coefficients isdoi:10.3991/ijoe.v9is6.2798 fatcat:jtotrrbrybch3nwgim2hzjyuzu