Comparative thermodynamic analysis in solution of a next generation antibody mimetic to VEGF

Hanieh Khalili, Steve Brocchini, Peng Tee Khaw, Sergey K. Filippov
2018 RSC Advances  
ITC illustrated similar binding thermodynamics for anti-VEGF IgG and FpFs. Bivalent FpFrani displayed larger enthalpy and entropy than monovalent ranibizumab.
doi:10.1039/c8ra07059h fatcat:m6olxdyvlvffnnh525bkf2thim