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Patient consent: Informed consent has been obtained from the patient's parent for publication of the case report. Dear editor, We report a new adverse event of diazoxide, e.g. a severe pericardial effusion, in a 15-monthold girl with Kabuki syndrome. We performed, for the first time, a causality assessment of this drug toxicity and found a high probability of a causal relationship between diazoxide and pericardial effusion. Indeed, after the treatment was suspended, the pericardial effusiondoi:10.4274/jcrpe.0193 fatcat:bsmrletgozgnhje24v3j2ibrdm