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Small nucleolar RNAs (snoRNAs) are an ancient class of small non-coding RNAs present in all eukaryotes and a subset of archaea that carry out a fundamental role in the modification and processing of ribosomal RNA. In recent years, however, a large proportion of snoRNAs have been found to be further processed into smaller molecules, some of which display different functionality. In parallel, several studies have uncovered extensive similarities between snoRNAs and other types of small non-codingdoi:10.1016/j.biochi.2011.05.026 pmid:21664409 pmcid:PMC3476530 fatcat:i7quds3yfrhr5khyumtex5de6a