A STUDY OF HISTOPATHOLOGICAL AND BIOCHEMICAL CHANGES OF LIVER IN TUBERCULOSIS
English

Kalinga Bommankatte Eranaik, Santosh Vastrad, Basangouda Sangangouda Patil
2017 Journal of Evidence Based Medicine and Healthcare  
BACKGROUND Infection with mycobacterium tuberculosis is most often found in well-oxygenated areas of the body such as the apices of the lung and renal cortex, it does affect liver in many ways. This kind of infection in the liver is usually secondary from TB of the lung or other organ. The aim of this study is to assess the liver function test abnormalities and histopathological changes on liver biopsy in tuberculosis and to correlate with biochemical and histopathological changes in
more » ... anges in tuberculosis patients. MATERIALS AND METHODS This cross-sectional observational study was carried out on 50 cases of tuberculosis patients admitted in medical wards at KIMS Hospital, Hubli. Out of 50 study participants, 40 were suffering from pulmonary and remaining 10 from disseminated tuberculosis. The need for liver biopsy was clinically assessed by the evaluating hepatologist following a complete physical examination and appropriate radiological imaging. Vitamin K 5 mg/day was given IM for three consecutive days prior to liver biopsy ruling out all contraindications and coagulation or bleeding disorders. Financial or Other, Competing Interest: None.
doi:10.18410/jebmh/2017/445 fatcat:lucqfidjfvafzklhytl52w4dq4