Insulin-secreting β-cell neoplasia in a 7-year-old female dog, case report and review

Edwin Aihanuwa Uwagie-Ero, Cheh Augustine Awasum, Chiamaka Onyejiakor, Eugene Amienwanlen Odigie, Daniel Osakpamwen Asemota, Pedro González-Redondo
2017 Cogent Food & Agriculture  
A 7-year-old female dog presented with intermittent episodes of urinary incontinence, tremors, intermittent episodes of pelvic limb weakness and collapse, and lethargy were noticed over a period of two months. Hypoglycaemia, secondary to an insulin-secreting β-cell tumour, was suspected on the basis of clinical signs, ultrasound and serum biochemistry. A laparotomy was then performed to remove the tumour mass. Post-surgical pancreatitis was a major complication. Histology revealed a malignant
more » ... ealed a malignant neuroendocrine neoplasia of the β-cells of the pancreas. This case review is reported to keep clinicians abreast of the canine insulinoma disorder and the complications surrounding its diagnosis and treatment.
doi:10.1080/23311932.2017.1293467 fatcat:ysywdnx3grbr3jbbjlcd3celu4