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Objective: To evaluate anemia as a cause of clinical disability in blood donors in the state of Maranhão- Brazil. Methods: This study addresses a time series of prevalence of anemia among blood donor candidates. Secondary data were collected from the Information System of the Blood Center of Maranhão. Donor candidates were treated between 2001 and 2010. Statistical analysis was performed with Epi Info version 6.04d. Results: The proportion of clinical disability was 16.8% (n = 1,672) and 63.27%doi:10.11606/issn.2176-7262.v51i3p189-196 fatcat:ksv4g2h3hnguzjpex5xiwzj3n4