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Extracellular ATP (eATP) can function as a signaling molecule to regulate a wide range of cellular processes. We investigated the regulatory role of eATP in the cell death induced by salicylic acid (SA) in suspension-cultured tobacco (Nicotiana tabacum L.) cells. Treatment of tobacco suspension cells with SA induced cell death. The same treatment lowered the levels of eATP, accompanied by a decrease of both the respiratory O 2 uptake and intracellular ATP levels in tobacco suspension cells.doi:10.1626/pps.18.154 fatcat:65ddqq2gvbf6be7xp7qvs36g44