Analysis of Foreign Journals: Journal de Chimie.--Gazette Medicale de Paris

1841 BMJ (Clinical Research Edition)  
The method first proposed by M. Lassaigne for the separation of small quantities of arsenic fromii animal tissues, was to add a weak alkaline solution to the mass of solids or liquids in which the arsenic was supposed to be contained, and then submit them to a gentle heat, so as to destroy and carbonise a portion of the organic nmatter. The product, when acted on by boiling water, conitains arsenite of potass, the presence of wlichl cani be readily detected by Marsh's apparatus, or by passing
more » ... us, or by passing the gas through a solution of nitrate of silver. In order to test the value of this method in cases of pDoisoning, several experiments were made on dogs, from which the author draws the following conclusions: 1. That the method proposed enables uis to determine the existence of small quantities of arsenic in the liver, heart, kidnies, &c. of animals, destroyed by arsenice 2. That a quantitive analysis of the liver of a dog, poisoned by fifty parts of arsenic, showed that, withiin an hour and a half after the administration of the poison, 17 parts were contained in the tissues of the liver. 3. 'Ifhat solid alsenious acidl acts v-ery feebly, but when diltuted wvith water, it acts more readily and with some degree of energy. The method of M. Lassaigne -above alluded to is as follows -The gas which is disengaged from MIarsh's apparatus is passed into a solution of pure nitrate of silver; the arsenuretted hydrogen, W'hich is mixed wvith hydrogen gas is thius gradually decomposed by the oxide of silver. The fluid now becomes broown; the metallic silver separates in the form of dark flocci, anid arsenious acid is produced, which remains in solution, mnixed;with an excess of nitrate of silver.
doi:10.1136/bmj.s1-1.23.377 fatcat:pkzp7yk5nvd65abfuqwtevuypy