Serum Vitamin D Levels and Severity of Liver Dysfunction in Cirrhotic Patients

Kambiz Yazdanpanah, Farshad Sheykhesmeeili, Baran Parhizkar, Abbas Ghasemi
2017 International journal of clinical medicine  
and objective: Cirrhosis affects hundreds of millions of patients all around the world. Vitamin D deficiency is frequently observed in chronic hepatic disease. Vitamin D level may be an important survival marker in advanced liver cirrhosis. Material and Methods: The study is a sectional one of the descriptive-analytical type, where 90 of the patients with hepatic cirrhoses were selected with census sampling method. In all the cirrhotic patients, for diagnosis in clinical findings, the
more » ... ings, the serological marker, autoantibodies were stable; biochemical endoscopy and imaging were the histological evidence and examinations and were then analyzed by SPSS version 22 software. Results: Based on the study, from the aspect of Child-Pugh classification, the highest vitamin D levels had the highest value in Child-Pugh class A with a frequency of 13 (43%) in the form of insufficiency, and had the highest value in Child-Pugh class B and C in the form of slight deficiency. Conclusion: It was specified based on the results obtained from the research that different vitamin D levels and liver failure severity have a significant relationship with each other (p < 0.05) in patients suffering from hepatic cirrhosis, such that the serum vitamin D level decreases as liver failure severity increases.
doi:10.4236/ijcm.2017.86038 fatcat:k6np6eostjd4lhz5vx6vdx5vcq