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Pathophysiology of obstructive sleep apnea-associated hypertension There is a well established relationship between the obstructive sleep apnea syndrome and hypertension. Current evidence suggests that the increase in arterial pressure is secondary to an enhanced sympathetic tone through peripheral chemoreflexes triggered by intermittent hypoxic stimulation of the carotid bodies. Chronic intermittent hypoxia would activate renal and systemic vasoactive systems through potentiated hypoxicdoi:10.4067/s0034-98872007001000016 fatcat:wdnnkd33tfftzkoe54aanvelp4