The article considers the quality of life of population and the impact of man-made accidents and disasters during stable functioning of industrial enterprises. The author offered to take into account the influence of anthropogenic factors, the source of which is industrial production, provoking man-made accidents and catastrophes, when assessing the quality of life of population. To fully take into account the factors affecting the quality of life of population, a comprehensive methodology

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... ed by the Council for the Study of Productive Forces by order of the Ministry of Economic Development of the Russian Federation that contains 19 indicators for diagnosing the quality of life of the population of the region, grouped by seven main areas, was chosen. Changes in the system of indicators of the consolidated index of the quality of life of the population under the influence of man-made accidents and catastrophes in the context of 7 spheres are shown. As an example, the impact on the main components of the quality of life of the population of the largest man-made disaster in the history of mankind and the nuclear industry - the Chernobyl accident - is considered.