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Epigenetic memory in gene regulation and immune response
Cells must fine-tune their gene expression programs for optimal cellular activities in their natural growth conditions. Transcriptional memory, a unique transcriptional response, plays a pivotal role in faster reactivation of genes upon environmental changes, and is facilitated if genes were previously in an active state. Hyper-activation of gene expression by transcriptional memory is critical for cellular differentiation, development, and adaptation. TREM (Transcriptional REpression Memory),doi:10.5483/bmbrep.2019.52.2.257 fatcat:7z2wadog6vdklbodtbft2fojbq