Treatment of Hepatitis C in Special Conditions: Liver Cirrhosis

Geum-Youn Gwak
2015 Korean Journal of Medicine  
Acquiring a sustained virological response (SVR) in patients with cirrhosis or advanced hepatic fibrosis reduces liver disease-related mortality and the incidence of hepatocellular carcinoma. However, the SVR rate of the current standard of care, which is combination therapy with peg-interferon-alpha and ribavirin, is significantly lower, and treatment-related complications occur more frequently in patients with cirrhosis. Thus, antiviral treatment should be individualized in this population.
more » ... this population. This review highlights the issues associated with anti-hepatitis C virus treatment in patients with compensated and decompensated cirrhosis. (Korean J Med 2015;88:643-646)
doi:10.3904/kjm.2015.88.6.643 fatcat:ynr6bmyibrehbkomvdtszixarq