Late Ovarian and Intestinal Extramedullary Relapse of Acute Myeloid Leukemia with Inv 16 after Allogeneic Hematopoietic Stem Cell Transplantation

Mensah Glanowska P
2018 Annals of Hematology & Oncology  
Treatment of acute myeloid leukemia (AML) extramedullary relapse (EMR) after allogenic hematopoietic stem cell transplantation (alloHSCT) is challenging. EMR pathogenesis of this entity is not clearly elucidated. Variety of factors affect clinical approaches in diagnostics, treatment and prognosis. Furthermore, there is no current consensus for post-transplant AML EMR treatment. We present here the case of young AML female patient with rare EMR presentation: ovary and large intestine
more » ... n. The treatment combined different strategiesconservative like surgery and chemotherapy, but also effective new approaches of targeted therapy -hypomethylating agent with tyrosine kinase inhibitor.
doi:10.26420/annhematoloncol.2018.1199 fatcat:k6vwi3hdzfhwbnsq5lwez3vdgm