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the brain and nervous system in our more malignant periodical fevers, before they become complicated with extensive local inflammation, is the very point on which the case is to turn for life or death. And the success of this treatment, in preference to the actual depletory system, is certainly very abundantly established. By it we immediately arrest tho paroxysm, and with the arrest of the paroxysm, we generally have an improvement of the symptoms. The pulse, instead of being small, quick anddoi:10.1056/nejm184712080371905 fatcat:2whxit6oaffkvkxhycftrg75h4