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Mortality from breast cancer decreased in high-income countries, while countries with middle and low incomes as Brazil still has upward trend. However, large geographical variations among the federal units are observed in the country. The aim of the study was to evaluate the trend of specific mortality from breast cancer in women over 20 years old years among different states of Brazil from 1996 to 2012. Methods and Findings: Ecological study, using linear regression model for temporal analysisdoi:10.3823/2282 fatcat:qmq3kbnuujewfmf6neersfz7q4