Efficacy of Ropivacaine and Bupivacaine on Postoperative Analgesia through Epidural Route in Spine Surgeries- A Comparative Clinical Study

Dr Chilaka Murali
2019 Journal of Medical Science And clinical Research  
This study was conducted to compare the post-operative analgesic efficacy and safety of Bupivacaine and Ropivacaine through epidural route after spine surgeries. It includes 100 patients, randomly allocated into two groups B & R, 50 patients for each group. Patients with ASA class I and II between the age of 18 and 60 years of both sexes were included. Group B patients received Bupivacaine 0.125%, 2ml/ segment and Group R patient received Ropivacaine 0.2% 2ml/segment, depending on incision
more » ... ng on incision length. The difference in mean baseline VAS score between the two groups was not found to be statistically significant. A VAS score of 0 reached at 22 mins in Ropivacaine compared to 24 mins in group Bupivacaine and lasted till 90 minutes as compared to 28 minutes in group B. thereafter also higher mean VAS scores were observed in group B (Bupivacaine) until the entire period of observation (240 minutes). Ropivacaine was found to be significantly more effective onset of analgesia (5.36±1.30 min and7.32±2.03min) peak level of analgesia (17.22±2.30 min and 21.36±2..54). And requirement of supplemental analgesia less than bupivacaine. Motor blockade assessed by the mean modified Bromage score was significantly less in Group Ropivacaine as compared to that observed in group Bupivacaine. These drugs were comparable in terms of haemodynamic parameters. This study concludes that Ropivacaine 0.2% was more efficient analgesic than Bupivacaine 0.125% in epidural anaesthesia.
doi:10.18535/jmscr/v7i6.32 fatcat:s2of73z5r5hhpbgfuwugtugr6q