Inhibition of peptidoglycan synthesis ofStreptococcus faecium ATCC 9790 andStreptococcus mutans BHT by the antibacterial agent dodecyl glycerol

H. S. Ved, Evan Gustow, Ronald A. Pieringer
1984 Bioscience Reports  
Dodecyl glycerol inhibits the synthesis of the peptidoglycans of Streptococcus faecium ATCC 9790 and Streptococcus mutans BHT. This metabolic regulation represents the second known mode by which dodecyl glycerol expresses antibacterial activity. The first mode of action of dodecyl glycerol was shown to stimulate autolysin activity which degrades cell-wall peptidoglycan (Ved HS9 Gustow E~ Mahadevan V and Pieringer RA~ 198#~ 3. Biol. Chem. 259, gi15-8121).
doi:10.1007/bf01121019 pmid:6437455 fatcat:xlqgvi3jznaurh3xnx4sf45qmi