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Understanding the mechanism of transit of a nanoparticle (NP) through a biomimetic bilayer has been at the forfront of research for the design of efficient drug-delivery mechanisms, nanotechnology and biomedicine. Establishing a consistent picture of how the transit mechanism depends on the physiochemical property of a NP is critical to understanding what approach may be the most effective for nanomedicine design. In this study, using molecular simulation techniques, we have analyzed the keydoi:10.26434/chemrxiv.11926938.v2 fatcat:rp6l4q7ugrekzdvikjk5ls74zq