1911 Archives of Pediatrics & Adolescent Medicine  
It is the purpose of this paper to present, in rather broad outlines, the part which mineral salts play in carrying on the physiologic functions of the body, and in what manner they contribute to the various pathologic processes to which the infant and young child are subjected. This field of metabolic research has been the last to be undertaken, and just now we are coming to realize its vast importance, not only in connection with their own functions, but in connection with the influence they
more » ... the influence they have on the metabolism of fat, protein and carbohydrate. The chief reason for having failed to realize the importance of the mineral salts in metabolism is that it has long been thought that the salts contributed in no way to the nourishment of the child. It has been only recently that they have taken their rightful place as indirect energy producers. HISTORICAL The first investigator to concern himself with the value of mineral salts was von Liebig,1 who, as early as 1840, studied the action of mineral salts both in animal and vegetable life, and many of his early deductions have become firmly fixed as laws in the field of mineral salts metabolism. C. Voit2 is another investigator whose work on the action of sodium ehlorid, as early as 1860, first gave to that salt its prominence above all others in the human economy. Vierordt was also an indefatigable worker, and as early as 1877, from meager data then present, had calculated absolute and relative heat and estimated child's metabolism. J. Forster,3 in 1873, added his convincing experiments on the necessity of the mineral salts to the continuance of life, and these were further reinforced by the work of Lunin4 in 1881. As time advanced, the roster of those who worked in the field of mineral metabolism contains the names of many Read, by invitation, before the meeting of the American Pediatric Society,
doi:10.1001/archpedi.1911.04100080044006 fatcat:argi6zs77rc5vczak2dcjg2mam