Dynamics of high-sensitivity cardiac troponin T during therapy with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension

Steffen D. Kriechbaum, Christoph B. Wiedenroth, Till Keller, Jan Sebastian Wolter, Ruth Ajnwojner, Karina Peters, Moritz A. Haas, Fritz C. Roller, Andreas Breithecker, Andreas J. Rieth, Stefan Guth, Andreas Rolf (+5 others)
2018 PLoS ONE  
Aims Balloon pulmonary angioplasty (BPA) is an interventional treatment modality for inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Therapy monitoring, based on non-invasive biomarkers, is a clinical challenge. This post-hoc study aimed to assess dynamics of high-sensitivity cardiac troponin T (hs-cTnT) as a marker for myocardial damage and its relation to N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels as a marker for cardiac wall stress. Dynamics of
more » ... mics of high-sensitivity cardiac troponin T during therapy with balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension. PLoS ONE 13(9): e0204683. https:// Funding: The authors received no specific funding for this work. decrease. The hs-cTnT levels correlated with the PVR (r rs = 0.42; p = 0.005), the meanPAP (r rs = 0.32; p = 0.029) and the NT-proBNP (r rs = 0.51; p<0.001) levels at BL.
doi:10.1371/journal.pone.0204683 fatcat:upgrfmcz5ze5neqa3r5rdevq7u