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Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project
2006
Nature Biotechnology
Microarray-based expression profiling experiments typically use either a one-color or a two-color design to measure mRNA abundance. The validity of each approach has been amply demonstrated. Here we provide a simultaneous comparison of results from one-and two-color labeling designs, using two independent RNA samples from the MicroArray Quality Control (MAQC) project, tested on each of three different microarray platforms. The data were evaluated in terms of reproducibility, specificity,
doi:10.1038/nbt1242
pmid:16964228
fatcat:flc6h5nienao3h7ceagi3vmh64