Rapid assessment of the IL-6 cervico-vaginal fluid level in threatening preterm labor
Szybka ocena stezenia IL-6 w wydzielinie szyjkowo-pochwowej w zagrazajacym porodzie przedwczesnym

Rafał Rzepka, Andrzej Torbé, Ryszard Czajka, Sebastian Kwiatkowski, Małgorzata Bartoszek, Aneta Cymbaluk
2009 Ginekologia Polska  
The aim of the study was to check the cervico-vaginal fluid IL-6 levels using rapid, quantitive test in patients with threatening preterm labor before and after tocolytic treatment. Sixty seven singular pregnant women, between 24 and 36 weeks of gestation, were included into the clinical trial. 35 women who were admitted to the Department due to clinical symptoms of threatened preterm labor formed the study group. 32 women between 24 and 36 gestational week, with uncomplicated pregnancy formed
more » ... d pregnancy formed the control group. Levels of IL-6 were measured just after material collection, using fast, quantitative spectrofotometric test. The cervico-vaginal IL-6 level was higher in the study group (458 pg/mL vs 123 pg/mL; p < 0.05). A significant reduction of cervico-vaginal IL-6 level was observed after two days of tocolytic treatment. A bedside, quantitative spectrofotometric method allows for a quick and repeatable assessment of cervico-vaginal IL-6 levels to establish the risk of preterm labor as well as enables the monitoring of the effectiveness of tocolytic treatment.
pmid:19886241 fatcat:nt7wkdyj3jh75nwecg4pbn42hq