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Results of the man age ment of rec tal can cer have enor mously im proved over the last al most forty years, by the pro gres sive de vel op ment of new inte grated treat ment op tions. nev er the less an op timi za tion of the re sults is needed to raise the still sub-op ti mal out come in terms of sur vival. sev eral na tional and in ter na tional guide lines ad dress the best treat ment choice over all eval u at ing the ev idence ba sis avail able from lit er a ture. Still a cer tain de greedoi:10.2298/aci1402009v fatcat:meiqbwza65glrdlz47one3uvoq