Force Sensing for the Identification of Single-Cell Microorganisms

A.S. Lee, M. Mahapatro, A.A.G. Requicha, M.E. Thompson, C. Zhou
The First IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, 2006. BioRob 2006.  
Identification of cells of a specific type is a fundamental problem both for laboratory analysis and for future nanorobots operating in physiological environments for health care applications. This paper shows that force sensing with Atomic Force Microscopes by using tips functionalized with antibodies is an effective technique for detecting microorganisms that cannot be identified by optical microscopy. Experimental results are presented for the identification of Brown Tide Algae, which are
more » ... glecell marine microorganisms with dimensions on the order of 1-2 micrometers, and for several control experiments.
doi:10.1109/biorob.2006.1639058 fatcat:mf6636u64ng6xnywbrqvzefzqi