Animal Experimentation

1923 Boston Medical and Surgical Journal  
In this paper we propose a new way of conceptualizing animals in experimentation: the animal-as-patient. Construing and treating animals as patients offers a way of successfully addressing some of the entrenched epistemological and ethical problems within a practice of animal experimentation directed to human clinical benefit. This approach is grounded in an epistemological insight and builds on work with so-called "pet models". It relies upon the occurrence and characterization of analogous
more » ... ion of analogous human and nonhuman animal diseases, where, if certain criteria of homology and mechanism are met, the animal simultaneously becomes a patient and a spontaneous model of the human disease.
doi:10.1056/nejm192301111880208 fatcat:ea33pyzmdvh77pgrauowzh22om