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The characteristics of water diffusional permeability (P) of human red blood cells were studied on isolated erythrocytes by a doping nuclear magnetic resonance technique. In order to estimate the basal permeability the maximal inhibition of water diffusion was reduced by exposure of red blood cells to p-chloromercuribenzene sulfonate (PCMBS) under various conditions (concentration, duration, temperature). The lowest values of P were around 0.7 x 10-3cms -1 at 10~ 1.2• 10-3cms -1 at 15~ 1.4xdoi:10.1007/bf01116848 pmid:2160303 fatcat:2zdvyl5fi5ddxonv4hkrqkjlri