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Variability of restriction fragments and copy number of the ribosomal DNA among four laboratory strains of the medaka (Oryzias latipes)
2003
Journal of Advanced Science
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We investigated variability in the size of restriction fragments of the rDNA region among 4 laboratory strains of the freshwater fish medaka including two wild-type fish and two pigmentation mutants. For this analysis, PCR-amplified 18S rDNA was used as a probe. DNA from 6 individuals of each strain was analyzed and significant variability in the restriction fragments was observed. The copy number of the 18S rDNA determined by dot-blot hybridization was also highly variable among individuals,
doi:10.2978/jsas.15.93
fatcat:5shpppdelnhabnax23akritvry