Structural Alterations of the Choroid Evaluated by Enhanced-Depth Imaging Optical Coherence Tomography in Patients with COVID-19 [post]

Özkan KOCAMIŞ, Emine Temel, Lokman HIZMALI, Nazife AŞIKGARİP, Kemal ÖRNEK, Fikriye Milletli Sezgin
2020 unpublished
Background: To assess alterations of choroid by enhanced depth imaging optical coherence tomography (EDI-OCT) in coronavirus disease 2019 (COVID-19).Methods: Thirty-two patients with COVID-19 infection (group 1) and 34 healthy subjects (group 2) were included in this study. The choroidal thickness was measured at three points: Subfoveal, 1500 mm nasal from the fovea, and 1500 mm temporal from the fovea. Total choroidal area, luminal area, stromal area and choroidal vascular index (CVI) was
more » ... ndex (CVI) was measured by Image-J.Results: In group 1, subfoveal, nasal, and temporal choroid thicknesses were thinner compared to group 2. However, there was no statistical significance (p=0.534, p=0.437, and p=0.077, respectively). The mean total choroidal area, the mean stromal area, the mean luminal area, and the mean CVI were significantly decreased in group 1 (p<0.001, p=0.001, p=0.001, and p=0.003; respectively).Conclusions: Our results demonstrate that there may be choroidal vascular and stromal depletion in these patients.
doi:10.21203/rs.3.rs-97433/v1 fatcat:vrjcxh2bfjeivnhdk3xtfg74y4