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The authors studied the process of perforation of soft biological tissue by continuous near infrared lasers (0.98 µm, 1.56 µm and 1.94 µm) with optic fiber delivery. Fiber drag force (FDF) during perforation of soft biological tissue was studied. Specific characteristics of laser radiation heat impact on the tissues surrounding the laser channel were examined. Three perforation modes were observed: mechanical perforation mode, intense evaporation and tissue destruction mode, "free" perforationdoi:10.18287/jbpe18.04.030301 fatcat:ek53zl346nblnpzcqqhta6kqeq