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Introduction/Objective Alpha-1 antitrypsin deficiency is a well established inherited risk factor for chronic obstructive pulmonary disease (COPD); however, alpha-1 antitrypsin level may result in different lung function reduction. The aim of our study was to evaluate possible associations of alpha-1 antitrypsin level and lung function in COPD patients with different alpha-1 antitrypsin phenotypes. Methods Serum alpha-1 antitrypsin concentration from patients (n = 1,167) with COPD, defineddoi:10.2298/sarh160809148s fatcat:lnxejh6zgffanivxwqjr6all2u