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Glioblastoma multiforme (GBM) is a class of devastating, highly aggressive central nervous system tumours. While the classical appearance is easily recognisable, several variations occur. We present 6 cases of confirmed GBM that illustrate the unusual findings in histological subtypes, early presentation and spread on MRI imaging.doi:10.4102/sajr.v16i3.289 fatcat:igoqbvifrrfhlfzqaj3gqurmyu