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Formulation and in Vitro Characterisation of Self Emulsifying Drug Delivery System of Diclofenac for the Enhancement of Dissolution and Solubility
2017
International Journal for Research in Applied Science and Engineering Technology
Diclofenac , non-steroidal anti-inflammatory drug (NSAID) belongs to BCS Class II drug with low dissolution and poor aqueous solubility. The main aim of the present study was to improve the solubility and dissolution rate of diclofenac using self-emulsifying drug delivery technique. Micro emulsion region was formed by preparing the ternary phase diagram. Ratio 0.15:0.85 , 0.5:0.5 and 0.3:0.7 was selected as the self-emulsification region for the development of formulation . Drugexcipient
doi:10.22214/ijraset.2017.2101
fatcat:dc5pdtdwcvcntporuelxzamyaq