Hyponatremia-induced Seizures in Schizophrenic Patient Treated with Olanzapine

Min Ku Kim, Se Jin Lee
2018 Journal of the Korean Neurological Association  
Severe hyponatremia (serum sodium concentration <120 mEq/L) is a well-known etiology of acute symptomatic seizure. Severe hyponatremia may occur as a rare but clinically important adverse reaction of psychotrophic drugs. Among them, patients with psychogenic polydipsia have especially higher risk of severe hyponatremia. We present a schizophrenic patient with polydipsia who developed severe hyponatremia and symptomatic seizures while receiving olanzapine treatment.
doi:10.17340/jkna.2018.2.4 fatcat:6a5kh5wzgja2xbmsp5o3eyn5fe