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Blood group A phenotype development is associated with impaired formation of adaptive and innate immunoglobulins due to clonal selection and phenotypic, glycosidic accommodation of plasma proteins. Moreover, it is significantly burdened with an increased risk of developing different types of cancer, while exerting strong susceptibility to severe malaria infection. Both the risk of developing cancer and susceptibility to malaria disease appear molecularly to be strongly related to phenotypedoi:10.6084/m9.figshare.4714618.v166 fatcat:6g3irrjnfjagbn5stnb5ifvcmu