The clinical and microbiological correlates of premature rupture of membranes

C Karat, P Madhivanan, K Krupp, S Poornima, NV Jayanthi, JS Suguna, E Mathai
2006 Indian Journal of Medical Microbiology  
Prematurity is the cause of 85% of neonatal morbidity and mortality. Premature rupture of the membranes (PROM) is associated with 30-40% of preterm deliveries. A case-control study conducted between July 2002 and 2003 examined the correlates and risk factors for PROM in Mysore, India. WBCs in vaginal fluid, leucocytes in urine, UTI and infection with E. coli, S. aureus, C. albicans and BV were significantly associated with PROM. BV, E. coli and WBCs in vaginal fluid were independent risk
more » ... pendent risk factors. Screening and treatment of BV and E. coli infection in pregnancy may reduce the risk of PROM.
doi:10.4103/0255-0857.29388 pmid:17185848 fatcat:n65qcj4kqnetjd4ijysuurbypy