Effect of Immunomodulator "Immunobeta" on Humoral Innate and Acquired Immune Response in Layer Hens

Nadya Bozakova
2018 Pakistan Veterinary Journal  
The effect of immunomodulator "Immunobeta" was investigated on 6750 layers hybrid Loman Brown divided in two equal groupscontrol and experimental. The layers were housed in enriched cages constructed in large battery for 3375 hensone for each group. The experiment started when hens were at 18 weeks of age. The control hens received the usual diet for their age, whereas the experimental birds received a diet supplemented with "Immunobeta" at a dosage of 4 kg/tone for 2 months. The first analysis
more » ... The first analysis was conducted prior to treatment (Test I), while the second study was done at the end of treatment, i.e. 2 months later (Test II). The evaluation of residual effect of the immunomodulatory substance was checked one month after the end of treatment (Test III). Twelve hens from each group were analysed in each test. The results indicated that "Immunobeta" increased lysozyme concentration in blood sera and hens' egg white. It was found that "Immunobeta" elevated the activity of alternative pathway of complement activation and increase the concentration of IgM as well. To Cite This Article: Bozakova N, Sotirov L, Koynarski T and Gundasheva D, 2018. Effect of immunomodulator "Immunobeta" on humoral innate and acquired immune response in layer hens. Pak Vet J, 38(4): 438-441. http://dx.
doi:10.29261/pakvetj/2018.070 fatcat:nslrfmzjcvefnedegdb6nvl7wu