Antiproliferative Activity Evaluation of a Series ofN-1,3-Benzothiazol-2-ylbenzamides as Novel Apoptosis Inducers

Filomena Corbo, Alessia Carocci, Domenico Armenise, Nicolino De Laurentis, Antonio Laghezza, Fulvio Loiodice, Patrizia Ancona, Marilena Muraglia, Vincenzo Pagliarulo, Carlo Franchini, Alessia Catalano
2016 Journal of Chemistry  
A series ofN-1,3-benzothiazol-2-ylbenzamide derivatives were studied for their antiproliferative activity on human liver hepatocellular carcinoma (HepG2) and human breast cancer (MCF-7) cell lines. Most of them were found to show a prominent inhibitory effect on cell growth. Among the most active compounds,1kemerged for its proapoptotic effect that is particularly evident towards MCF-7 cancer cell lines.
doi:10.1155/2016/4267564 fatcat:5ttxwmv4obcrzfq75hfacsg47q