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Liposome has been studied as a potential carrier for targeting and controlled drug delivery. However, poor stability remains a challenge because it can lead to drug leakage from the vesicles thus reduce the effectiveness towards the target cell. For this aim, the present study incorporated the low molecular weight chitosan (LMWC) into the oleic acid liposome to maintain the stability and prolong the lifetime in the blood circulation. The thin-film hydration method was employed to prepare thedoi:10.17576/jsm-2020-4909-20 fatcat:wpcgp2lsarcnfdlhkgpm4v567e