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Scaffolds that serve as synthetic mimics of the extracellular matrix have applications in wound healing, tissue engineering, and stem cell expansion. When cells are cultured in these tunable matrices, little is known about local microenvironmental changes during degradation and remodeling. Methods that provide quantitative and predictable information about cell-mediated remodeling could significantly improve the biomaterial design process. We use passive microrheology, a technique that measuresdoi:10.1073/pnas.ss11229 fatcat:lxaeklxi3jgnrjflwnelqtxfsu